Showing Protein Lysophosphatidic acid receptor 4 (CDBP02550)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 2 compounds
Identification
HMDB Protein ID CDBP02550
Secondary Accession Numbers Not Available
Name Lysophosphatidic acid receptor 4
Description Not Available
Synonyms
  1. G-protein coupled receptor 23
  2. LPA receptor 4
  3. LPA-4
  4. P2Y purinoceptor 9
  5. P2Y5-like receptor
  6. P2Y9
  7. Purinergic receptor 9
Gene Name LPAR4
Protein Type Receptor
Biological Properties
General Function Involved in G-protein coupled receptor protein signaling pathway
Specific Function Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1- alkyl- > 1-alkenyl-LPA
GO Classification
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
nucleotide receptor activity, g-protein coupled
purinergic nucleotide receptor activity, g-protein coupled
receptor activity
transmembrane receptor activity
molecular transducer activity
signal transducer activity
g-protein coupled receptor activity
Process
signaling pathway
cell surface receptor linked signaling pathway
g-protein coupled receptor protein signaling pathway
signaling
Cellular Location
  1. Cell membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs LPAR4
Gene Sequence 
>1113 bp
ATGGGTGACAGAAGATTCATTGACTTCCAATTCCAAGATTCAAATTCAAGCCTCAGACCC
AGGTTGGGCAATGCTACTGCCAATAATACTTGCATTGTTGATGATTCCTTCAAGTATAAT
CTCAATGGTGCTGTCTACAGTGTTGTATTCATCTTGGGTCTGATAACCAACAGTGTCTCT
CTGTTTGTCTTCTGTTTCCGCATGAAAATGAGAAGTGAGACTGCTATTTTTATCACCAAT
CTAGCTGTCTCTGATTTGCTTTTTGTCTGTACACTACCTTTTAAAATATTTTACAACTTC
AACCGCCACTGGCCTTTTGGTGACACCCTCTGCAAGATCTCTGGAACTGCATTCCTTACC
AACATCTATGGGAGCATGCTCTTTCTCACCTGTATTAGTGTGGATCGTTTCCTGGCCATT
GTCTATCCTTTTCGATCTCGTACTATTAGGACTAGGAGGAATTCTGCCATTGTGTGTGCT
GGTGTCTGGATCCTAGTCCTCAGTGGCGGTATTTCAGCCTCTTTGTTTTCCACCACTAAT
GTCAACAATGCAACCACCACCTGCTTTGAAGGCCTCTCCAAACGTGTCTGGAAGACTTAT
TTATCCAAGATCACAATATTTATTGAAGTTGTTGGGTTTATCATTCCTCTAATATTGAAT
GTCTCTTGCTCTTCTGTGGTGCTGAGAACTCTTCGCAAGCCTGCTACTCTGTCTCAAATT
GGGACCAATAAGAAAAAAGTACTGAAAATGATCACAGTACATATGGCAGTCTTTGTGGTA
TGCTTTGTACCCTACAACTCTGTCCTCTTCTTGTATGCCCTGGTGCGCTCCCAAGCTATT
ACTAATTGCTTTTTGGAAAGATTTGCAAAGATCATGTACCCAATCACCTTGTGCCTTGCA
ACTCTGAACTGTTGTTTTGACCCTTTCATCTATTACTTCACCCTTGAATCCTTTCAGAAG
TCCTTCTACATCAATGCCCACATCAGAATGGAGTCCCTGTTTAAGACTGAAACACCTTTG
ACCACAAAGCCTTCCCTTCCAGCTATTCAAGAGGAAGTGAGTGATCAAACAACAAATAAT
GGTGGTGAATTAATGCTAGAATCCACCTTTTAG
Protein Properties
Number of Residues 370
Molecular Weight 41894.7
Theoretical pI 9.28
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["44-64", "74-94", "113-133", "156-176", "204-224", "255-275", "295-315"]
Protein Sequence 
>Lysophosphatidic acid receptor 4
MGDRRFIDFQFQDSNSSLRPRLGNATANNTCIVDDSFKYNLNGAVYSVVFILGLITNSVS
LFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFKIFYNFNRHWPFGDTLCKISGTAFLT
NIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGVWILVLSGGISASLFSTTN
VNNATTTCFEGFSKRVWKTYLSKITIFIEVVGFIIPLILNVSCSSVVLRTLRKPATLSQI
GTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALVRSQAITNCFLERFAKIMYPITLCLA
TLNCCFDPFIYYFTLESFQKSFYINAHIRMESLFKTETPLTTKPSLPAIQEEVSDQTTNN
GGELMLESTF
GenBank ID Protein 2240035
UniProtKB/Swiss-Prot ID Q99677
UniProtKB/Swiss-Prot Entry Name LPAR4_HUMAN
PDB IDs Not Available
GenBank Gene ID AF005419
GeneCard ID LPAR4
GenAtlas ID LPAR4
HGNC ID HGNC:4478
References
General References Not Available